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Find clinical trials for Alzheimer's Disease in Cleveland, OH

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Psychomotor Agitation
Brain Diseases
Neurodegenerative Diseases

Alzheimer's Disease trials near Cleveland, OH, USA:

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)

This is a randomized, double-blind, sham-controlled, adaptive-design pivotal study of sensory stimulation in subjects with mild to moderate Alzheimer's...

Enrolling
Alzheimer Disease 6
Dementia of Alzheimer Type
Device: Sensory Stimulation System (GS120) - Sham
Device: Sensory Stimulation System (GS120) - Active
Cognito Therapeutics
Cognito Therapeutics

Beachwood, Ohio, United States and 67 other locations

on the change from baseline at 6 months in cerebrospinal fluid (CSF) microtubule-binding region (MTBR)-tau-243 in participants with early Alzheimer's...

Enrolling
Alzheimer's Disease
Drug: E2814
Drug: Lecanemab

Phase 2

Eisai
Eisai

Cleveland, Ohio, United States and 33 other locations

Locations recently updated

This is a master protocol for 3 independent, seamlessly enrolling, multicenter, randomized, double-blind, placebo-controlled, parallel-group studies...

Enrolling
Alzheimer's Disease Psychosis
Drug: Placebo
Drug: ACP-204

Phase 2, Phase 3

Acadia Pharmaceuticals
Acadia Pharmaceuticals

Beachwood, Ohio, United States and 105 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Cleveland, Ohio, United States and 117 other locations

administered once every four weeks (Q4W) in slowing cognitive and functional decline as compared to placebo in participants with early Alzheimer's...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: sabirnetug

Phase 2

Acumen Pharmaceuticals

Cleveland, Ohio, United States and 96 other locations

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Placebo
Drug: Lecanemab

Phase 3

Eisai
Eisai

Cleveland, Ohio, United States and 246 other locations

The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (inclu...

Enrolling
Alzheimer's Disease
Drug: GSK4527226
Other: Placebo

Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

North Canton, Ohio, United States and 103 other locations

study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants with Early Alzheimer's...

Enrolling
Alzheimer Disease, Early Onset
Other: Placebo
Drug: BMS-986446

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Beachwood, Ohio, United States and 203 other locations

in adults with mild cognitive impairment (MCI) or mild-to-moderate Alzheimer's Disease (AD). The primary hypothesis (Part 1) is tha...

Enrolling
Alzheimer Disease
Drug: Placebo
Biological: MK-2214

Phase 1

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

North Canton, Ohio, United States of America and 11 other locations

of emraclidine administered orally to healthy elderly participants in Part A (multiple ascending doses) and participants with dementia due to Alzheimer's...

Enrolling
Alzheimer's Disease Dementia
Healthy Participants
Drug: Placebo
Drug: Emraclidine

Phase 1

Cerevel Therapeutics
Cerevel Therapeutics

North Canton, Ohio, United States and 10 other locations

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