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is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...
Phase 3
Montreal, Quebec, Canada and 111 other locations
be from 2 clinical subgroups: mild cognitive impairment (MCI) due to Alzheimer's disease (AD) or mild Alzheimer's disease...
Phase 2
Montreal, Quebec, Canada and 168 other locations
This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...
Phase 3
Greenfield Park, Quebec, Canada and 246 other locations
administered once every four weeks (Q4W) in slowing cognitive and functional decline as compared to placebo in participants with early Alzheimer's...
Phase 2, Phase 3
Greenfield Park, Quebec, Canada and 124 other locations
The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (inclu...
Phase 2
Greenfield-Park, Quebec, Canada and 103 other locations
study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants with Early Alzheimer's...
Phase 2
Montreal, Quebec, Canada and 183 other locations
The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on clinical decline as measured by the Integrated Alzheimer's...
Phase 2
Montreal, Quebec, Canada and 122 other locations
In this study, researchers will learn more about a study drug called BIIB080. The study will focus on participants with mild cognitive impairment or...
Phase 2
Montréal, Quebec, Canada and 133 other locations
as measured by changes in the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) score as compared with placebo in participants with early Alzheimer's...
Phase 3
Greenfield-Park, Quebec, Canada and 210 other locations
The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease...
Phase 3
Greenfield Park, Quebec, Canada and 275 other locations
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