Find clinical trials for Asthma in Louisville, KY

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Asthma trials near Louisville, KY, USA:

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma (EXHALE-4)

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Active, not recruiting

Asthma Attack

Asthma; Eosinophilic

Drug: Dexpramipexole Dihydrochloride

Drug: Placebo

Phase 3

Areteia Therapeutics

Louisville, Kentucky, United States and 335 other locations

A Study to Investigate the Effect on Lung Function of BDA Formulated With a Next Generation Propellant Compared With an Approved Asthma Treatment (BDA With HFA Propellant) in Participants With Asthma

The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed repl....

Active, not recruiting

Asthma

Drug: BDA MDI HFO 160/180 μg

Drug: BDA MDI HFA 160/180 μg

Phase 3

AstraZeneca

Louisville, Kentucky, United States and 127 other locations

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma (AIM4:Next Step)

This study is researching a drug called dupilumab. The study is focused on patients who have uncontrolled asthma. Asthma is a condi...

Active, not recruiting

Asthma

Drug: dupilumab

Drug: Matching Placebo

Phase 4

Regeneron Pharmaceuticals

Louisville, Kentucky, United States and 77 other locations

A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma (BREADTH)

This Phase 2b study is designed to evaluate the safety and efficacy of KT-621 in participants with uncontrolled moderate to severe eosinophilic asthma...

Enrolling

Eosinophilic Asthma

Drug: KT-621

Other: Placebo

Phase 2

Kymera Therapeutics

Louisville, Kentucky, United States and 57 other locations

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

ANCHOR is a prospective, phase IV, interventional, single-arm, open-label study of 1,500 adult participants with symptomatic asthma requirin...

Active, not recruiting

Asthma

Drug: Albuterol and budesonide inhalation aerosol

Phase 4

AstraZeneca

Louisville, Kentucky, United States and 10 other locations

Locations recently updated

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma (ACADIA)

MDI), both administered as needed, on the annualized rate of severe asthma exacerbations in adolescents with a documented clinical diagnosis...

Enrolling

Asthma

Combination Product: BDA MDI

Combination Product: AS MDI

Phase 3

AstraZeneca

Louisville, Kentucky, United States and 141 other locations

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids (Umbriel)

phase IIb study designed to assess efficacy and safety of tozorakimab administered subcutaneously in adult participants with uncontrolled asthma...

Enrolling

Asthma

Drug: Placebo

Drug: Tozorakimab

Phase 2

AstraZeneca

Louisville, Kentucky, United States and 212 other locations

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma (ATLAS)

decline in adult patients with uncontrolled moderate to severe asthma.The estimated duration is 4±1 weeks of screening and run-in period, fo...

Active, not recruiting

Asthma

Drug: Placebo

Drug: Dupilumab

Phase 4

Sanofi

Louisville, Kentucky, United States and 260 other locations

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids (Umbriel)

phase IIb study designed to assess efficacy and safety of tozorakimab administered subcutaneously in adult participants with uncontrolled asthma...

Not yet enrolling

Asthma

Drug: Placebo

Drug: Tozorakimab

Phase 2

AstraZeneca

Louisville, Kentucky, United States and 150 other locations

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Find clinical trials for Asthma in .css-epvm6{white-space:nowrap;}Louisville, KY

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Asthma trials near Louisville, KY, USA:

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma (EXHALE-4)

A Study to Investigate the Effect on Lung Function of BDA Formulated With a Next Generation Propellant Compared With an Approved Asthma Treatment (BDA With HFA Propellant) in Participants With Asthma

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma (AIM4:Next Step)

A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma (BREADTH)

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma (ACADIA)

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids (Umbriel)

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma (ATLAS)

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids (Umbriel)

Find clinical trials for Asthma in Louisville, KY