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Find clinical trials for Colon Cancer in Boston, MA

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Cancer
Neoplasm Metastasis

Colon Cancer trials near Boston, MA, USA:

Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases

This study seeks to learn more about the vitamin D receptor and its relationship to colon cancer. The Vitamin D receptor is found i ...

Enrolling
Stage, Colon Cancer
Stage IV Colon Cancer With Resectable Liver Metastases
Drug: Placebo
Drug: Vitamin D3

Early Phase 1

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States

and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...

Begins enrollment this month
Proficient Mismatch Repair (pMMR) Colon Cancer
Microsatellite Stable (MSS) Colon Cancer
Drug: Porustobart
Drug: Pembrolizumab

Phase 2

Solstice Oncology, Inc.

Boston, Massachusetts, United States and 29 other locations

This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept effi...

Active, not recruiting
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Boston, Massachusetts, United States and 10 other locations

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...

Active, not recruiting
Glioma
Chondrosarcoma
Drug: LY3410738
Drug: Gemcitabine

Phase 1

Lilly
Lilly

Boston, Massachusetts, United States and 32 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Active, not recruiting
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Boston, Massachusetts, United States and 85 other locations

care (FOLFOX plus bevacizumab) alone and in combination with novel oncology therapies in first-line metastatic microsatellite-stable colorectal cancer...

Active, not recruiting
Metastatic Microsatellite-stable Colorectal Cancer
Drug: FOLFOX
Drug: Bevacizumab

Phase 1, Phase 2

MedImmune
MedImmune

Providence, Rhode Island, United States and 20 other locations

This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 16 other locations

This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012,...

Enrolling
Advanced Cancer
Colon Cancer
Drug: PHN-012

Phase 1

Pheon Therapeutics

Boston, Massachusetts, United States and 25 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Boston, Massachusetts, United States and 1076 other locations

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236

Phase 1, Phase 2

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 20 other locations

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