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Find clinical trials for Colon Cancer in Boston, MA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Lung Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Adenocarcinoma

Colon Cancer trials near Boston, MA, USA:

Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases

This study seeks to learn more about the vitamin D receptor and its relationship to colon cancer. The Vitamin D receptor is found i ...

Enrolling
Stage, Colon Cancer
Stage IV Colon Cancer With Resectable Liver Metastases
Drug: Placebo
Drug: Vitamin D3

Early Phase 1

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States

dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, an...

Active, not recruiting
Any Solid Tumor
Glioma
Drug: LY3410738
Drug: Gemcitabine

Phase 1

Lilly
Lilly

Boston, Massachusetts, United States and 32 other locations

is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 16 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Boston, Massachusetts, United States and 83 other locations

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236

Phase 1

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 15 other locations

This study is to evaluate the safety, tolerability, and PK profiles of RMC-6291 and RMC-6236 in adults with KRAS G12C-mutated solid tumors....

Enrolling
Non-Small Cell Lung Cancer (NSCLC)
Colorectal Cancer
Drug: Assigned interventions

Phase 1

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 27 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Enrolling
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Boston, Massachusetts, United States and 25 other locations

This study will test the safety of a drug called SGN-EGFRd2 in participants with advanced solid tumors. It will also study the side effects ...

Enrolling
Colorectal Neoplasms
Squamous Cell Carcinoma of the Head and Neck
Drug: SGN-EGFRd2

Phase 1

Seagen
Seagen

Boston, Massachusetts, United States and 12 other locations

inhibitor) monotherapy in adult subjects with advanced solid tumors and to identify the maximum tolerated dose (MTD), and the recommended Ph...

Active, not recruiting
Colorectal Cancer (CRC)
Advanced Solid Tumor
Drug: RMC-6291

Phase 1

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 63 other locations

Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of CO...

Enrolling
Advanced Cancer
Colon Cancer
Drug: Cohort expansion: COM902 (RDFE) monotherapy.
Combination Product: Cohort expansion: Triplet combination of COM902 + COM701 + Pembrolizumab.

Phase 1

Compugen

Boston, Massachusetts, United States and 8 other locations

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