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Find clinical trials for Colon Cancer in Boston, MA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Neoplasm Metastasis
Pancreatic Cancer

Colon Cancer trials near Boston, MA, USA:

Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases

This study seeks to learn more about the vitamin D receptor and its relationship to colon cancer. The Vitamin D receptor is found i ...

Enrolling
Stage, Colon Cancer
Stage IV Colon Cancer With Resectable Liver Metastases
Drug: Placebo
Drug: Vitamin D3

Early Phase 1

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States

of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/β-catenin signaling pathw...

Enrolling
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Boston, Massachusetts, United States and 10 other locations

is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 16 other locations

dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, an...

Active, not recruiting
Any Solid Tumor
Glioma
Drug: LY3410738
Drug: Gemcitabine

Phase 1

Lilly
Lilly

Boston, Massachusetts, United States and 32 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Boston, Massachusetts, United States and 85 other locations

This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the s...

Enrolling
Colorectal Neoplasms
Squamous Cell Carcinoma of the Head and Neck
Drug: PF-08046052

Phase 1

Seagen, a wholly owned subsidiary of Pfizer

Boston, Massachusetts, United States and 23 other locations

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236

Phase 1

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 15 other locations

Locations recently updated

The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumors with KRAS mutation...

Enrolling
Advanced Solid Tumors
CRC (Colorectal Cancer)
Drug: ALTA3263

Phase 1

Alterome Therapeutics, Inc.

Boston, Massachusetts, United States and 6 other locations

This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of ....

Active, not recruiting
Advanced Cancer
Endometrial Cancer
Drug: PHN-010

Phase 1

Pheon Therapeutics

Boston, Massachusetts, United States and 7 other locations

in combination with pembrolizumab in patients with select advanced cancers, and to identify the maximum tolerated dose and/or recommended do...

Enrolling
Anal Cancer
Triple Negative Breast Neoplasms
Drug: pembrolizumab
Drug: KFA115

Phase 1

Novartis
Novartis

Boston, Massachusetts, United States and 18 other locations

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