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This study seeks to learn more about the vitamin D receptor and its relationship to colon cancer. The Vitamin D receptor is found i ...
Early Phase 1
Boston, Massachusetts, United States
and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...
Phase 2
Boston, Massachusetts, United States and 29 other locations
This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept effi...
Phase 1
Boston, Massachusetts, United States and 10 other locations
This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...
Phase 1
Boston, Massachusetts, United States and 32 other locations
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
Boston, Massachusetts, United States and 85 other locations
care (FOLFOX plus bevacizumab) alone and in combination with novel oncology therapies in first-line metastatic microsatellite-stable colorectal cancer...
Phase 1, Phase 2
Providence, Rhode Island, United States and 20 other locations
This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...
Phase 1
Boston, Massachusetts, United States and 16 other locations
This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012,...
Phase 1
Boston, Massachusetts, United States and 25 other locations
the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...
Phase 2, Phase 3
Boston, Massachusetts, United States and 1076 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Phase 1, Phase 2
Boston, Massachusetts, United States and 20 other locations
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