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with panitumumab in subjects with unresectable, refractory, KRAS/NRAS/BRAF wild-type, microsatellite stable (MSS) metastatic colorectal cancer...
Phase 2
Indianapolis, Indiana, United States and 4 other locations
dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, an...
Phase 1
Indianapolis, Indiana, United States and 32 other locations
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...
Phase 2, Phase 3
Indianapolis, Indiana, United States and 878 other locations
known as MVC-101) in adults with unremovable advanced or metastatic cancer. Another aim is to characterize and evaluate the activity of TAK-...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 19 other locations
the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ABM-168 in adult patients with RAS or RAF or NF-1 mutated ...
Phase 1
Indianapolis, Indiana, United States and 5 other locations
of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected Stage II/III rectal cancer...
Phase 2
Indianapolis, Indiana, United States and 112 other locations
Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...
Phase 3
Indianapolis, Indiana, United States and 282 other locations
a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...
Phase 3
Indianapolis, Indiana, United States and 989 other locations
versus a fluoropyrimidine/bevacizumab alone as assessed by molecular response which is based on changes in circulating tumor (ct)DNA. The...
Phase 2, Phase 3
Indianapolis, Indiana, United States and 42 other locations
This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to ...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 12 other locations
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