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and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...
Phase 2
Los Angeles, California, United States and 29 other locations
(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
Los Angeles, California, United States and 262 other locations
with histologically or cytologically confirmed stage IV colorectal cancer coming form three different patient populations:* Cohort 1a: 6 pat...
Phase 1
Los Angeles, California, United States and 11 other locations
Solid tumours are abnormal lumps of tissue that can occur in different parts of the body. The tumours involved in this study have specific genetic ch...
Phase 1, Phase 2
Los Angeles, California, United States and 21 other locations
This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept effi...
Phase 1
Los Angeles, California, United States and 10 other locations
RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of existing...
Phase 1
Los Angeles, California, United States and 2 other locations
activity of CBI-1214 in participants with advanced or metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer...
Phase 1
Los Angeles, California, United States and 9 other locations
This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...
Phase 1
Los Angeles, California, United States and 32 other locations
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
Los Angeles, California, United States and 85 other locations
care (FOLFOX plus bevacizumab) alone and in combination with novel oncology therapies in first-line metastatic microsatellite-stable colorectal cancer...
Phase 1, Phase 2
Los Angeles, California, United States and 20 other locations
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