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Find clinical trials for Colon Cancer in Los Angeles, CA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Neoplasm Metastasis
Adenocarcinoma

Colon Cancer trials near Los Angeles, CA, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Los Angeles, California, United States and 250 other locations

with histologically or cytologically confirmed stage IV colorectal cancer coming form three different patient populations:* Cohort 1a: 6 pat...

Active, not recruiting
Stage IV Rectal Cancer
Metastatic Colorectal Cancer
Drug: ATP128
Drug: BI 754091

Phase 1

Amal Therapeutics

Los Angeles, California, United States and 11 other locations

of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/β-catenin signaling pathw...

Enrolling
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Los Angeles, California, United States and 6 other locations

(PK) of BBO-8520, a KRAS G12C (ON) inhibitor, single agent and in combination with pembrolizumab in patients with advanced non-small cell lung cancer...

Enrolling
Colon Cancer
Metastatic Colon Cancer
Drug: BBO-8520
Drug: Pembrolizumab

Phase 1

TheRas, Inc., d/b/a BridgeBio Oncology Therapeutics

Santa Monica, California, United States and 14 other locations

and pembrolizumab) given together for the treatment of colorectal cancer that:* is metastatic (spread to other parts of the body);* has the ...

Active, not recruiting
Metastatic Colorectal Cancer
Biological: Pembrolizumab
Biological: Cetuximab

Phase 2

Pfizer
Pfizer

Los Angeles, California, United States and 111 other locations

dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, an...

Active, not recruiting
Any Solid Tumor
Glioma
Drug: LY3410738
Drug: Gemcitabine

Phase 1

Lilly
Lilly

Los Angeles, California, United States and 32 other locations

trial determining the efficacy of adjuvant trifluridine and tipiracil (TAS-102) in combination with irinotecan in patients with ctDNA positive colon...

Enrolling
Colorectal Cancer
Colon Adenocarcinoma
Diagnostic Test: Signatera MRD ctDNA Assay
Combination Product: Standard Treatment

Phase 1

University of California Irvine (UCI)
University of California Irvine (UCI)

Orange, California, United States

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Los Angeles, California, United States and 83 other locations

RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of...

Enrolling
Colon Cancer
Lung Cancer
Drug: RSC-1255 Dose Expansion
Drug: RSC-1255 Dose Escalation

Phase 1

Rascal Therapeutics

Los Angeles, California, United States and 4 other locations

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236

Phase 1

Revolution Medicines
Revolution Medicines

Santa Monica, California, United States and 15 other locations

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