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Find clinical trials for Heart Disease in Orlando, FL

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Coronary Disease

Heart Disease trials near Orlando, FL, USA:

Locations recently updated

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure (INNOVATE)

non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart...

Enrolling
Cardiovascular Diseases
Heart Failure
Device: BrioVAD System
Device: HeartMate 3
BrioHealth Solutions, Inc.

Orlando, Florida, United States and 10 other locations

) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...

Invitation-only
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Orlando, Florida, United States and 60 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Orlando, Florida, United States and 103 other locations

of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...

Enrolling
Heart Valve Diseases
Cardiovascular Diseases
Other: Guideline Directed Heart Failure Medication
Device: Carillon Mitral Contour System
Cardiac Dimensions

Orlando, Florida, United States and 71 other locations

To establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve (THV) in patients with severe, calcific aortic s...

Active, not recruiting
Aortic Stenosis
Procedure: SAVR
Device: SAPIEN 3 THV
Edwards Lifesciences
Edwards Lifesciences

Orlando, Florida, United States and 76 other locations

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications o...

Enrolling
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Orlando, Florida, United States and 834 other locations

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Active, not recruiting
Cardiovascular Disease
Drug: Cagrilintide
Drug: Semaglutide

Phase 3

Novo Nordisk
Novo Nordisk

Mount Dora, Florida, United States and 569 other locations

The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease...

Active, not recruiting
Atherosclerotic Cardiovascular Disease
Drug: Olpasiran
Drug: Placebo

Phase 3

Amgen
Amgen

Orlando, Florida, United States and 737 other locations

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. ...

Enrolling
Acute Myocardial Infarction (AMI)
Cardiovascular Risk
Drug: Ziltivekimab
Drug: Placebo

Phase 3

Novo Nordisk
Novo Nordisk

Winter Haven, Florida, United States and 783 other locations

cardiovascular events (MACE) including coronary heart disease (CHD) death, ischemic stroke, myocardial infarction (MI), acute limb...

Active, not recruiting
Arteriosclerosis
Hypercholesterolaemia
Drug: Placebo
Drug: Enlicitide Decanoate

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Winter Park, Florida, United States and 672 other locations

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