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of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...
Orlando, Florida, United States and 61 other locations
The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease...
Phase 3
Orlando, Florida, United States and 467 other locations
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...
Orlando, Florida, United States and 103 other locations
To establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve (THV) in patients with severe, calcific aortic s...
Orlando, Florida, United States and 76 other locations
The purpose of the study is to demonstrate the long term safety and effectiveness of the Carpentier-Edwards® PERIMOUNT Magna Mitral Valves in patient...
Orlando, Florida, United States and 14 other locations
Various patient groups with the On-X Valve can be maintained safely on lower doses of blood thinner(Coumadin®) or on antiplatelet drugs (aspirin/Plav...
Orlando, Florida, United States and 48 other locations
This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults wi...
Phase 3
Winter Park, Florida, United States and 851 other locations
The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipi...
Phase 4
Orlando, Florida, United States and 119 other locations
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the cl...
Phase 3
Orlando, Florida, United States and 173 other locations
The objective of this study is to evaluate the effects of sotatercept (MK-7962, formerly called ACE-011) treatment (plus maximum tolerated background...
Phase 3
Orlando, Florida, United States and 56 other locations
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