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Find clinical trials for Melanoma in Seattle, WA

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Melanoma trials near Seattle, WA, USA:

Locations recently updated

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...

Enrolling
Melanoma
Unresectable Melanoma
Biological: Pembrolizumab with Optional Crossover Period
Biological: Lifileucel plus Pembrolizumab

Phase 3

Iovance Biotherapeutics

Edmonds, Washington, United States and 53 other locations

and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + tram...

Enrolling
Advanced or Metastatic NRAS-mutant Melanoma
Drug: Trametinib
Drug: Naporafenib

Phase 3

Erasca

Seattle, Washington, United States and 44 other locations

Locations recently updated

efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma...

Enrolling
Ocular Melanoma
Choroidal Melanoma
Device: Suprachoroidal Microinjector
Drug: Bel-sar

Phase 3

Aura Biosciences
Aura Biosciences

Seattle, Washington, United States and 46 other locations

The purpose of this study is to assess the patient's preference for nivolumab subcutaneous (SC) or nivolumab + relatlimab fixed-dose combination (FDC...

Active, not recruiting
Melanoma
Drug: nivolumab+rHuPH20
Drug: relatlimab+nivolumab

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Seattle, Washington, United States and 31 other locations

artery infusion of SD-101, a TLR 9 agonist, alone or in combination with intravenous checkpoint blockade in adults with metastatic uveal melanoma...

Active, not recruiting
Metastatic Uveal Melanoma in the Liver
Biological: Nivolumab
Drug: SD-101

Phase 1

TriSalus Life Sciences

Seattle, Washington, United States and 9 other locations

with relapsed or refractory (R/R) metastatic or locally advanced melanoma, non-small cell lung cancer (NSCLC), and colorectal cancer (CRC)....

Active, not recruiting
Melanoma
Non-small Cell Lung Cancer
Biological: LYL845

Phase 1

Lyell Immunopharma

Seattle, Washington, United States and 17 other locations

(IMC-F106C) plus nivolumab compared to standard nivolumab regimens in HLA-A\*02:01-positive participants with previously untreated advanced melanoma...

Enrolling
Advanced Melanoma
Biological: Brenetafusp
Biological: Nivolumab + Relatlimab

Phase 3

Immunocore
Immunocore

Seattle, Washington, United States and 97 other locations

This study will test the safety of a drug called PF-08046049/SGN-BB228 in participants with melanoma and other solid tumors that are hard to...

Enrolling
Cutaneous Melanoma
Non-small Cell Lung Cancer
Drug: PF-08046049

Phase 1

Seagen
Seagen

Seattle, Washington, United States and 21 other locations

(PROs) of autogene cevumeran (RO7198457) plus pembrolizumab compared with pembrolizumab alone in patients with previously untreated advanced melanoma...

Active, not recruiting
Advanced Melanoma
Drug: Pembrolizumab
Biological: Autogene cevumeran

Phase 2

Genentech
Genentech

Seattle, Washington, United States and 56 other locations

placebo in participants with surgically resected high-risk Stage II melanoma. Participants in Part 1 will receive either pembrolizumab or pl...

Active, not recruiting
Melanoma
Other: Placebo
Biological: Pembrolizumab

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Seattle, Washington, United States and 158 other locations

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