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The purpose of this clinical study is to confirm the utility of chemosensitivity (ChemoID) tumor testing on cancer stem cells as a ...
Phase 3
Pittsburgh, Pennsylvania, United States and 7 other locations
using CPI-0209 in combination with Carboplatin chemotherapy followed by CPI-0209 maintenance in patients with platinum sensitive, recurrent ovarian...
Phase 1
Pittsburgh, Pennsylvania, United States
after frontline treatment with platinum-based therapy in advanced ovarian cancer patients with BRCAwt, homologous recombination def...
Phase 2
Pittsburgh, Pennsylvania, United States
cancer). This Phase III trial builds on the efficacy and safety data reported in the previous Phase II VIRO-15 trial with promising objecti ...
Phase 3
Pittsburgh, Pennsylvania, United States and 25 other locations
study with safety lead in of oral talazoparib in combination with ZEN003694 given daily in 28-day cycles will enroll patients with recurrent ovarian...
Phase 2
Pittsburgh, Pennsylvania, United States
followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian ...
Phase 3
Pittsburgh, Pennsylvania, United States and 213 other locations
IP rintatolimod (TLR-3 agonist) and IV infusion of the checkpoint inhibitor pembrolizumab (IVP) for patients with recurrent platinum-sensitive ovarian...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States
This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...
Phase 3
Pittsburgh, Pennsylvania, United States and 63 other locations
of a chemokine modulatory (CKM) regimen composed of a cocktail of IP rintatolimod and interferon-alpha (IFNα) for patients with advanced stage ovarian...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 1 other location
This is a Phase 2, open-label, randomized, 3-arm study to evaluate progression-free survival (PFS) in patients with recurrent platinum-resistant ovarian...
Phase 2
Pittsburgh, Pennsylvania, United States and 20 other locations
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