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Find clinical trials for Ovarian Cancer in Pittsburgh, PA

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Related conditions:

Ovarian Epithelial Carcinoma
Cancer
Carcinoma
Endometrial Cancer
Fallopian Tube Cancer
Breast Cancer
Triple Negative Breast Cancer

Ovarian Cancer trials near Pittsburgh, PA, USA:

Cancer Stem Cell Assay Directed Chemotherapy in Recurrent Platinum Resistant Ovarian Cancer

The purpose of this clinical study is to confirm the utility of chemosensitivity (ChemoID) tumor testing on cancer stem cells as a ...

Active, not recruiting
Recurrent Ovarian Carcinoma
Platinum-resistant Ovarian Cancer
Diagnostic Test: ChemoID Assay
Drug: Standard Chemotherapy

Phase 3

Cordgenics

Pittsburgh, Pennsylvania, United States and 7 other locations

using CPI-0209 in combination with Carboplatin chemotherapy followed by CPI-0209 maintenance in patients with platinum sensitive, recurrent ovarian...

Enrolling
Recurrent Ovarian Cancer
Drug: CPI-0209
Drug: carboplatin

Phase 1

Lan Coffman

Pittsburgh, Pennsylvania, United States

cancer). This Phase III trial builds on the efficacy and safety data reported in the previous Phase II VIRO-15 trial with promising objecti ...

Enrolling
Primary Peritoneal Cancer
Platinum-refractory Ovarian Cancer
Drug: Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin
Drug: Platinum chemotherapy: carboplatin (preferred) or cisplatin

Phase 3

Genelux

Pittsburgh, Pennsylvania, United States and 29 other locations

study with safety lead in of oral talazoparib in combination with ZEN003694 given daily in 28-day cycles will enroll patients with recurrent ovarian...

Enrolling
Peritoneal Cancer
Fallopian Tube Cancer
Drug: Talazoparib
Drug: ZEN003694

Phase 2

Alexander B Olawaiye, MD

Pittsburgh, Pennsylvania, United States

followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian ...

Active, not recruiting
Advanced Ovarian Cancer
Drug: Bevacizumab
Drug: Durvalumab placebo

Phase 3

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 213 other locations

IP rintatolimod (TLR-3 agonist) and IV infusion of the checkpoint inhibitor pembrolizumab (IVP) for patients with recurrent platinum-sensitive ovarian...

Active, not recruiting
Ovarian Cancer Recurrent
Drug: Cisplatin
Drug: Rintatolimod

Phase 1, Phase 2

Robert Edwards

Pittsburgh, Pennsylvania, United States

The purpose of this study is to assess the safety, tolerability, and efficacy of CBX-12 in female subjects with platinum resistant or refractory ovarian...

Enrolling
Refractory Ovarian Carcinoma
Platinum-resistant Ovarian Cancer
Drug: CBX-12

Phase 2

Cybrexa Therapeutics

Pittsburgh, Pennsylvania, United States and 19 other locations

This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...

Enrolling
Low Grade Serous Ovarian Cancer
Drug: Defactinib
Drug: Letrozole

Phase 3

Verastem

Pittsburgh, Pennsylvania, United States and 94 other locations

help researchers understand more fully whether this immune cell therapy, also known as CAR T cell therapy, can be safely used to treat solid tumors...

Enrolling
Epithelial Ovarian Cancer
Fallopian Tube Cancer
Drug: Cemiplimab
Other: 27T51

Phase 1

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 3 other locations

Immunotherapy with immune checkpoint inhibitors, including pembrolizumab, have emerged as a promising option in several solid cancers with d...

Enrolling
Ovarian Cancer
Drug: Pembrolizumab
Drug: Doxorubicin

Phase 2

Alexander B Olawaiye, MD

Pittsburgh, Pennsylvania, United States

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