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Find clinical trials for Ovarian Cancer in Pittsburgh, PA

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Related conditions:

Ovarian Epithelial Carcinoma
Cancer
Carcinoma
Endometrial Cancer
Fallopian Tube Cancer
Breast Cancer
Triple Negative Breast Cancer
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Ovarian Cancer trials near Pittsburgh, PA, USA:

The purpose of this clinical study is to confirm the utility of chemosensitivity (ChemoID) tumor testing on cancer stem cells as a ...

Active, not recruiting
Recurrent Ovarian Carcinoma
Platinum-resistant Ovarian Cancer
Diagnostic Test: ChemoID Assay
Drug: Standard Chemotherapy

Phase 3

Cordgenics

Pittsburgh, Pennsylvania, United States and 7 other locations

using CPI-0209 in combination with Carboplatin chemotherapy followed by CPI-0209 maintenance in patients with platinum sensitive, recurrent ovarian...

Enrolling
Recurrent Ovarian Cancer
Drug: CPI-0209
Drug: carboplatin

Phase 1

Lan Coffman

Pittsburgh, Pennsylvania, United States

cancer). This Phase III trial builds on the efficacy and safety data reported in the previous Phase II VIRO-15 trial with promising objecti ...

Enrolling
Primary Peritoneal Cancer
Platinum-refractory Ovarian Cancer
Drug: Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin
Drug: Platinum chemotherapy: carboplatin (preferred) or cisplatin

Phase 3

Genelux

Pittsburgh, Pennsylvania, United States and 29 other locations

study with safety lead in of oral talazoparib in combination with ZEN003694 given daily in 28-day cycles will enroll patients with recurrent ovarian...

Enrolling
Peritoneal Cancer
Fallopian Tube Cancer
Drug: Talazoparib
Drug: ZEN003694

Phase 2

Alexander B Olawaiye, MD

Pittsburgh, Pennsylvania, United States

followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian ...

Active, not recruiting
Advanced Ovarian Cancer
Drug: Bevacizumab
Drug: Durvalumab placebo

Phase 3

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 213 other locations

IP rintatolimod (TLR-3 agonist) and IV infusion of the checkpoint inhibitor pembrolizumab (IVP) for patients with recurrent platinum-sensitive ovarian...

Enrolling
Ovarian Cancer Recurrent
Drug: Cisplatin
Drug: Rintatolimod

Phase 1, Phase 2

Robert Edwards

Pittsburgh, Pennsylvania, United States

The purpose of this study is to assess the safety, tolerability, and efficacy of CBX-12 in female subjects with platinum resistant or refractory ovarian...

Enrolling
Refractory Ovarian Carcinoma
Platinum-resistant Ovarian Cancer
Drug: CBX-12

Phase 2

Cybrexa Therapeutics

Pittsburgh, Pennsylvania, United States and 19 other locations

of a chemokine modulatory (CKM) regimen composed of a cocktail of IP rintatolimod and interferon-alpha (IFNα) for patients with advanced stage ovarian...

Enrolling
Ovary Cancer
Ovary Neoplasms
Biological: Cisplatin + CKM + Celecoxib + DC Vaccine
Biological: Cisplatin + celecoxib + DC vaccine

Phase 1, Phase 2

Roswell Park Comprehensive Cancer Center
Roswell Park Comprehensive Cancer Center

Pittsburgh, Pennsylvania, United States and 1 other location

This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (I...

Enrolling
Low Grade Serous Ovarian Cancer
Drug: Defactinib
Drug: Letrozole

Phase 3

Verastem

Pittsburgh, Pennsylvania, United States and 87 other locations

This is a Phase 2, open-label, randomized, 3-arm study to evaluate progression-free survival (PFS) in patients with recurrent platinum-resistant ovarian...

Active, not recruiting
Recurrent Ovarian Cancer
Recurrent Primary Peritoneal Carcinoma
Drug: Relacorilant, 100mg QD
Drug: Relacorilant, 150mg QD

Phase 2

Corcept Therapeutics
Corcept Therapeutics

Pittsburgh, Pennsylvania, United States and 20 other locations