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receiving lower radiation doses, in patients with locally advanced pancreatic cancer, without increasing the rate of serious gastro...
Saint Louis, Missouri, United States and 12 other locations
of borderline-resectable, locally-advanced , or medically inoperable pancreatic adenocarcinoma will translate into a decreased toxicity. The...
Saint Louis, Missouri, United States
A Phase 1/1b dose finding study to determine the OBD(s) and RP2D(s) of BMF-219, a covalent menin inhibitor small molecule, in subjects with KRAS muta...
Phase 1
Saint Louis, Missouri, United States and 22 other locations
SOT102 administered as monotherapy (Part C) and in combination with first-line SoC treatment (Part D) in patients with advanced or metastatic pancreatic...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 7 other locations
in combination with gemcitabine and nab-paclitaxel in patients with Pancreatic Ductal Adenocarcinoma (PDAC) who have been previously untreat...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 10 other locations
This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 4 other locations
and clinical activity of AB680 in combination with Zimberelimab (AB122), nab-paclitaxel and gemcitabine in participants with advanced pancreatic...
Phase 1
Saint Louis, Missouri, United States and 17 other locations
The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall surviv...
Phase 2
Creve Coeur, Missouri, United States and 137 other locations
This trial will study tisotumab vedotin to find out whether it is an effective treatment alone or with other anticancer drugs for certain solid tumor...
Phase 2
Saint Louis, Missouri, United States and 64 other locations
The goal of this study is to test A2B530,an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorectal cancer...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 9 other locations
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