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receiving lower radiation doses, in patients with locally advanced pancreatic cancer, without increasing the rate of serious gastro...
Saint Louis, Missouri, United States and 12 other locations
of borderline-resectable, locally-advanced , or medically inoperable pancreatic adenocarcinoma will translate into a decreased toxicity. The...
Saint Louis, Missouri, United States
Zolbetuximab is being studied as a treatment for people with pancreatic cancer. Most people with pancreatic cancer...
Phase 2
Creve Coeur, Missouri, United States and 135 other locations
A Phase 1/1b dose finding study to determine the OBD(s) and RP2D(s) of BMF-219, a covalent menin inhibitor small molecule, in subjects with KRAS muta...
Phase 1
Saint Louis, Missouri, United States and 22 other locations
in combination with gemcitabine and nab-paclitaxel in patients with Pancreatic Ductal Adenocarcinoma (PDAC) who have been previously untreat...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 11 other locations
SOT102 administered as monotherapy (Part C) and in combination with first-line SoC treatment (Part D) in patients with advanced or metastatic pancreatic...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 7 other locations
phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...
Phase 1
Saint Louis, Missouri, United States and 55 other locations
This is a Phase 1b/2, open-label, multi-center, competitive enrollment and dose-escalation study of HCW9218 in patients with advanced/metastatic pancreatic...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 4 other locations
and clinical activity of AB680 in combination with Zimberelimab (AB122), nab-paclitaxel and gemcitabine in participants with advanced pancreatic...
Phase 1
Saint Louis, Missouri, United States and 17 other locations
The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adeno...
Phase 1
Saint Louis, Missouri, United States
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