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open label, multi-center, clinical study of Chimeric Antigen Receptor T Cells (CAR-T) targeting claudin18.2 in patients with advanced gastric, pancreatic...
Phase 1, Phase 2
Toronto, Ontario, Canada and 15 other locations
study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic...
Phase 2
Toronto, Ontario, Canada and 37 other locations
phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety...
Phase 1
Toronto, Ontario, Canada and 76 other locations
The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combinatio...
Phase 3
Toronto, Ontario, Canada and 81 other locations
The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.
Phase 3
Toronto, Ontario, Canada and 85 other locations
The purpose of this study is to evaluate the safety, tolerability, and efficacy of BMS-986523 alone and in combination with anti-cancer agen...
Phase 1, Phase 2
Toronto, Ontario, Canada and 7 other locations
of AZD0901 as monotherapy and in combination with anti-cancer agents in participants with locally advanced unresectable or metastatic solid ...
Phase 2
Toronto, Ontario, Canada and 51 other locations
The purpose of the study is to explore the safety and effects of the study drug (PF-08046876) in people diagnosed with advanced cancer of th...
Phase 1
Toronto, Ontario, Canada and 30 other locations
This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer age...
Phase 1, Phase 2
Toronto, Ontario, Canada and 67 other locations
This is a study designed to assess the safety, tolerability, pharmacokinetics and preliminary efficacy of WEF-001 as monotherapy in patients with Adv...
Phase 1, Phase 2
Toronto, Ontario, Canada and 3 other locations
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