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Find clinical trials for Pancreatic Cancer in Toronto, ON

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Toronto, ON, CAN:

Claudin18.2 CAR-T (CT041) in Patients with Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers

open label, multi-center, clinical study of Chimeric Antigen Receptor T Cells (CAR-T) targeting claudin18.2 in patients with advanced gastric, pancreatic...

Active, not recruiting
Gastric Cancer
Pancreatic Cancer
Biological: CT041

Phase 1, Phase 2

CARsgen Therapeutics

Toronto, Ontario, Canada and 15 other locations

Locations recently updated

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: AMG 193
Drug: Gemcitabine

Phase 1

Amgen
Amgen

Toronto, Ontario, Canada and 71 other locations

to participants. Part C will use the information from Parts A and B to see if PF-08046049/SGN-BB228 is safe and if it works to treat solid tumor...

Active, not recruiting
Non-small Cell Lung Cancer
Colorectal Neoplasms
Drug: PF-08046049

Phase 1

Seagen, a wholly owned subsidiary of Pfizer

Toronto, Ontario, Canada and 29 other locations

Status recently updated

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer age....

Enrolling
Active, not recruiting
Breast Cancer
Biliary Cancer
Drug: Camizestrant
Drug: T- Dxd

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 67 other locations

to assess the safety, tolerability, PK, PD, immunogenicity and anti-tumor activity of zenocutuzumab (MCLA-128) in patients with solid tumors...

Active, not recruiting
Pancreatic Cancer Harboring NRG1 Fusion
NSCLC Harboring NRG1 Fusion
Drug: zenocutuzumab (MCLA-128)

Phase 2

Partner Therapeutics

Toronto, Ontario, Canada and 63 other locations

This phase II trial studies cediranib maleate in combination with olaparib in treating patients with solid tumors that have spread to other ...

Active, not recruiting
Stage IV Pancreatic Cancer AJCC v6 and v7
Pancreatic Ductal Adenocarcinoma
Other: 18F-Fluoromisonidazole
Drug: Cediranib Maleate

Phase 2

National Cancer Institute (NCI)
National Cancer Institute (NCI)

Toronto, Ontario, Canada and 15 other locations

BOLD-100 is an intravenously administered sterile solution containing the ruthenium-based small molecule. BOLD-100 has been shown to preferentially d...

Enrolling
Gastric Cancers
Pancreatic Cancer
Drug: BOLD-100 in combination with FOLFOX Chemotherapy (Dose Expansion)
Drug: BOLD-100 in combination with FOLFOX Chemotherapy (Dose Escalation)

Phase 1, Phase 2

Bold Therapeutics

Toronto, Ontario, Canada and 13 other locations

of AZD0901 as monotherapy and in combination with anti-cancer agents in participants with locally advanced unresectable or metastatic solid ...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: l-leucovorin
Drug: Gemcitabine

Phase 2

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 49 other locations

biliary cancer that has spread to other organs. It is hoped that this new combination of drugs (nab-paclitaxel, gemcitabine, and cisplatin)...

Active, not recruiting
Unresectable Biliary Tract Cancer
Drug: nab-paclitaxel in combination with gemcitabine + cisplatin

Phase 2

AHS Cancer Control Alberta

Toronto, Ontario, Canada and 1 other location

Locations recently updated

deruxtecan (T-DXd) for the treatment of selected HER2-expressing tumors.This study will consist of Part 1 which includes 7 cohorts of: uroth ...

Enrolling
Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer
Drug: Trastuzumab deruxtecan

Phase 2

AstraZeneca
AstraZeneca

Hamilton, Ontario, Canada and 120 other locations

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