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Find clinical trials for Pancreatic Cancer in Toronto, ON

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Lung Cancer
Non-Small-Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Toronto, ON, CAN:

Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced Pancreatic Cancer (LAPIS)

with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of participants with locally advanced, unresectable pancreatic...

Active, not recruiting
Pancreatic Cancer Non-resectable
Drug: Pamrevlumab + Gemcitabine + Nab-paclitaxel or Pamrevlumab + FOLFIRINOX
Drug: Placebo + Gemcitabine + Nab-paclitaxel or Placebo + FOLFIRINOX

Phase 3

FibroGen
FibroGen

Toronto, Ontario, Canada and 89 other locations

open label, multi-center, clinical study of Chimeric Antigen Receptor T Cells (CAR-T) targeting claudin18.2 in patients with advanced gastric, pancreatic...

Active, not recruiting
Gastric Cancer
Pancreatic Cancer
Biological: CT041

Phase 1, Phase 2

CARsgen Therapeutics

Toronto, Ontario, Canada and 15 other locations

of AZD0901 as monotherapy and in combination with anti-cancer agents in participants with locally advanced unresectable or metastatic solid ...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: l-leucovorin
Drug: Gemcitabine

Phase 2

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 48 other locations

given to participants. Part C will use the information from Parts A and B to see if SGN-BB228 is safe and if it works to treat solid tumor cancers...

Enrolling
Non-small Cell Lung Cancer
Pancreatic Neoplasms
Drug: SGN-BB228

Phase 1

Seagen
Seagen

Toronto, Other, Canada and 18 other locations

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer age...

Enrolling
Breast Cancer
Biliary Cancer
Drug: Camizestrant
Drug: Paclitaxel

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 73 other locations

This is a Phase I/II, open-label, multi-center, multi-national, dose escalation, single agent study to assess the safety, tolerability, PK, PD, immun...

Enrolling
Pancreatic Cancer Harboring NRG1 Fusion
NSCLC Harboring NRG1 Fusion
Drug: zenocutuzumab (MCLA-128)

Phase 2

Merus

Toronto, Ontario, Canada and 64 other locations

or cannot be removed by surgery (unresectable), including breast cancer, non-small cell lung cancer, small cell lung cancer...

Active, not recruiting
Stage IV Pancreatic Cancer AJCC v6 and v7
Pancreatic Ductal Adenocarcinoma
Other: Laboratory Biomarker Analysis
Other: 18F-Fluoromisonidazole

Phase 2

National Cancer Institute (NCI)
National Cancer Institute (NCI)

Toronto, Ontario, Canada and 15 other locations

BOLD-100 is an intravenously administered sterile solution containing the ruthenium-based small molecule. BOLD-100 has been shown to preferentially d...

Active, not recruiting
Gastric Cancers
Pancreatic Cancer
Drug: BOLD-100 in combination with FOLFOX Chemotherapy (Dose Escalation)
Drug: BOLD-100 in combination with FOLFOX Chemotherapy (Dose Expansion)

Phase 1, Phase 2

Bold Therapeutics

Toronto, Ontario, Canada and 12 other locations

This is an open-label, multi-center, phase 1b study designed to determine a tolerable dose of CX-5461 administered by IV infusion on Day 1 and Day 8...

Enrolling
Advanced Solid Tumor
Drug: CX-5461

Phase 1

Senhwa Biosciences

Toronto, Ontario, Canada and 7 other locations

This is a first-in-human, Phase 1/2 study to evaluate LCB84, a TROP2-directed antibody-drug conjugate, alone and in combination with an anti-PD-1 Ab,...

Enrolling
Advanced Solid Tumors
Drug: Anti-PD-1 monoclonal antibody
Drug: LCB84

Phase 1, Phase 2

LigaChem Biosciences

Toronto, Ontario, Canada and 5 other locations

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