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Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatme ...
Phase 1
Maywood, Illinois, United States and 2 other locations
This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative b ...
Phase 2
Chicago, Illinois, United States and 9 other locations
The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer...
Phase 2
Chicago, Illinois, United States and 8 other locations
and to evaluate the efficacy of this combination in advanced HER2 negative breast cancer that is triple negative...
Phase 1, Phase 2
Chicago, Illinois, United States and 4 other locations
This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease after pre-operative therapy will be assigned to 1 of 3 Arms bas...
Phase 2
Chicago, Illinois, United States and 12 other locations
This trial studies ladiratuzumab vedotin (LV) with pembrolizumab in patients with triple-negative breast cancer. -...
Phase 1, Phase 2
Maywood, Illinois, United States and 49 other locations
This pilot study will provide preliminary data regarding the role of PIS in predicting the benefit of immune checkpoint inhibition with or without ch...
Phase 2
Chicago, Illinois, United States and 3 other locations
oral immuno-oncology product candidate targeting immune-suppressive tumor-associated myeloid cells through selective inhibition of phosphoin ...
Phase 2
Chicago, Illinois, United States and 23 other locations
doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC). Usually, after neoadjuvant therapy and surgery for triple ne ...
Phase 3
Chicago, Illinois, United States and 216 other locations
avelumab with sacituzumab govitecan works in treating patients with triple negative breast cancer that is stage I...
Phase 2
Evergreen Park, Illinois, United States and 11 other locations
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