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Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatme ...
Phase 1
Maywood, Illinois, United States and 2 other locations
This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative b ...
Phase 2
Chicago, Illinois, United States and 9 other locations
The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer...
Phase 2
Chicago, Illinois, United States and 8 other locations
and to evaluate the efficacy of this combination in advanced HER2 negative breast cancer that is triple negative...
Phase 1, Phase 2
Chicago, Illinois, United States and 4 other locations
This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease after pre-operative therapy will be assigned to 1 of 3 Arms bas...
Phase 2
Chicago, Illinois, United States and 12 other locations
oral immuno-oncology product candidate targeting immune-suppressive tumor-associated myeloid cells through selective inhibition of phosphoin ...
Phase 2
Chicago, Illinois, United States and 23 other locations
doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC). Usually, after neoadjuvant therapy and surgery for triple ne ...
Phase 3
Chicago, Illinois, United States and 216 other locations
avelumab with sacituzumab govitecan works in treating patients with triple negative breast cancer that is stage I...
Phase 2
Evergreen Park, Illinois, United States and 11 other locations
or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...
Phase 3
Chicago, Illinois, United States and 166 other locations
This study will assess the efficacy and safety of Niraparib in participants with either tumor mutation in the BRCA gene (tBRCAmut) HER2- breast...
Phase 3
Chicago, Illinois, United States and 199 other locations
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