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This trial studies ladiratuzumab vedotin (LV) with pembrolizumab in patients with triple-negative breast cancer. -...
Phase 1, Phase 2
Orlando, Florida, United States and 49 other locations
oral immuno-oncology product candidate targeting immune-suppressive tumor-associated myeloid cells through selective inhibition of phosphoin ...
Phase 2
Orlando, Florida, United States and 23 other locations
doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC). Usually, after neoadjuvant therapy and surgery for triple ne ...
Phase 3
Orlando, Florida, United States and 216 other locations
or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...
Phase 3
Orlando, Florida, United States and 165 other locations
previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors...
Phase 3
Orlando, Florida, United States and 516 other locations
with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors...
Phase 3
Orlando, Florida, United States and 505 other locations
with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...
Phase 3
Orlando, Florida, United States and 360 other locations
by the intravenous (IV) route to participants with solid tumors or lymphomas.The main goals of this study are to:* Find the recommended dose...
Phase 1, Phase 2
Orlando, Florida, United States and 9 other locations
preliminary antitumor activity of NKT3447 in adult subjects with cyclin E1 (CCNE1) amplified ovarian cancer at the RDEs selected in Dose Es...
Phase 1
Celebration, Florida, United States and 7 other locations
cancers.* Part D will find out if and how much SGN-B7H4V can be given with pembrolizumab.* Part E will use the amount found in Part D to fi ...
Phase 1
Orlando, Florida, United States and 18 other locations
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