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Find clinical trials for Triple Negative Breast Cancer in St Louis, MO

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Related conditions:

Breast Cancer
Non-Small-Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck
Ovarian Cancer
Cancer
Colorectal Cancer
Endometrial Cancer

Triple Negative Breast Cancer trials near St Louis, MO, USA:

Establishing the Recommended Biological Dose for AE37 Peptide Vaccine in Combination With Pembrolizumab That Will Enhance the Tumor-specific Immune Response and Demonstrate Efficacy in Patients With Advanced Triple-negative Breast Cancer (NSABP FB-14)

immune response and demonstrate efficacy in patients with advanced triple-negative breast cancer.This study will ...

Active, not recruiting
Triple-negative Breast Cancer
Biological: Pembrolizumab
Biological: AE37 Peptide vaccine

Phase 2

NuGenerex Immuno-Oncology

Swansea, Illinois, United States and 5 other locations

of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple...

Active, not recruiting
Triple Negative Breast Neoplasms
Drug: Capivasertib
Drug: Trastuzumab deruxtecan

Phase 1, Phase 2

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 31 other locations

(SG) given at an alternative dose and schedule, in participants with triple-negative breast cancer (TNBC).The pri...

Enrolling
Triple Negative Breast Cancer
Drug: Sacituzumab Govitecan-hziy (SG)

Phase 1, Phase 2

Gilead Sciences
Gilead Sciences

St Louis, Missouri, United States and 15 other locations

doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC). Usually, after neoadjuvant therapy and surgery for triple ne ...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Atezolizumab
Drug: Placebo

Phase 3

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Swansea, Illinois, United States and 216 other locations

and capecitabine) for the treatment of first-line metastatic triple-negative breast cancer (TNBC) or estrogen rec...

Enrolling
Breast Neoplasms
Drug: Paclitaxel
Drug: Iza-bren

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

O'Fallon, Illinois, United States and 294 other locations

or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...

Enrolling
Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)

Phase 3

Gilead Sciences
Gilead Sciences

St Louis, Missouri, United States and 372 other locations

with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...

Active, not recruiting
Breast Cancer
Drug: Pembrolizumab
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 275 other locations

Locations recently updated

This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without du...

Enrolling
Breast Cancer
Drug: Paclitaxel
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 315 other locations

A study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) an...

Active, not recruiting
Non-small-cell-lung-cancer (NSCLC)
Cancer
Drug: ABBV-368
Drug: ABBV-927

Phase 1

AbbVie
AbbVie

St Louis, Missouri, United States and 28 other locations

of NKT5097 in adults with advanced/metastatic tumors (emphasis on breast cancer and solid tumors with CCNE1 amplification). Main qu...

Enrolling
Triple Negative Breast Cancer (TNBC)
HR+ Breast Cancer
Drug: NKT5097 CDK2/CDK4 dual degrader
Drug: Fulvestrant

Phase 1

NiKang Therapeutics

St Louis, Missouri, United States and 17 other locations

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