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CenExel Clinical Research | JBR Clinical Research

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Top treatments

Acetaminophen
Ibuprofen
VX-548
Naproxen Sodium
HTX-011
Bupivacaine Hydrochloride
HSK3486
Propofol
Caffeine
Dexmedetomidine

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Active trials

13 of 54 total trials

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

This is a Phase 4, randomized, blinded, active-controlled, multicohort study to evaluate HTX-011 compared with bupivacaine HCl in subjects undergoing...

Active, not recruiting
Analgesia
Drug: Acetaminophen
Drug: HTX-011

The purpose of this study is to evaluate the safety, reactogenicity, and relative vaccine efficacy (rVE) of the mRNA-1283.222 vaccine as well as its...

Active, not recruiting
COVID-19
Biological: mRNA-1273.222
Biological: mRNA-1283.222

The study is divided into 2 parts: Part 1 and Part 2. The purpose of Part 1 of this study is to generate sufficient safety, reactogenicity, and immun...

Active, not recruiting
Influenza
SARS-CoV-2
Biological: mRNA-1083.3
Biological: Influenza Vaccine 1

The primary purpose of this study is to assess the efficacy and safety of the etonogestrel (ENG) contraceptive implant during participants' fourth an...

Active, not recruiting
Contraception
Combination Product: Radiopaque Etonogestrel (ENG) Implant

This study is being conducted to evaluate the efficacy and safety of ASA compared to placebo in the management of osteoarthritis (OA) symptoms of the...

Enrolling
Knee Osteoarthritis
Biological: Amniotic Suspension Allograft
Drug: Placebo

The purpose of this study is to evaluate the safety and immunogenicity of a single intramuscular (IM) injection of different formulations of Quadriva...

Active, not recruiting
Influenza Immunization
Biological: Quadrivalent Influenza mRNA Vaccine MRT5429
Biological: Quadrivalent Influenza mRNA Vaccine MRT5421

This is a phase IIa, randomized, double-blind, placebo-controlled, multi-center proof-of-concept (POC) study in subjects with moderate to severe Atop...

Enrolling
Atopic Dermatitis
Drug: ADX-914
Drug: Placebo

The purpose of the study is to evaluate the efficacy and safety of VX-548 in treating participants with PLSR.

Enrolling
Painful Lumbosacral Radiculopathy
Drug: VX-548
Drug: Placebo

The primary objective of this study is to evaluate the analgesic efficacy of DMTS, compared with placebo, in subjects following abdominoplasty.

Enrolling
Pain, Postoperative
Drug: Placebo Patch
Drug: DMTS Patch

The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of moderate or severe migraine in children and adolesc...

Enrolling
Acute Treatment of Migraine
Drug: Rimegepant / BHV3000

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in chil...

Enrolling
Pediatric Migraine
Drug: Rimegepant/BHV3000
Drug: Matching placebo

The purpose of this study is to evaluate the safety and blood levels of a medicine, naltrexone, contained within an implant in healthy volunteers age...

Invitation-only
Opioid Use Disorder
Device: BIOPIN-6 Placebo Implant
Combination Product: BIOPIN-6 Active Implant with Naltrexone

The purpose of the Phase 1 Part of this study is to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1403 and mRNA-1405 in healthy adu...

Active, not recruiting
Norovirus Acute Gastroenteritis
Biological: mRNA-1403
Biological: Placebo

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