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Eastern Shore Research Institute, LLC | Fairhope, AL

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Top treatments

Maridebart Cafraglutide
sodium
EVOLocumab
Inclisiran
Obicetrapib
CK-4021586
R2R01
Diuretic

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Active trials

7 of 12 total trials

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

CKJX839D12302 is a pivotal Phase III study designed to test the hypothesis that treatment with inclisiran sodium 300 milligram (mg) subcutaneous (s.c...

Active, not recruiting
Primary Prevention of Atherosclerotic Cardiovascular Disease
Drug: Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL
Drug: Placebo in 1.5ml

This is a Phase 2 dose-finding study in adult participants with symptomatic HFpEF.

Enrolling
Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Drug: CK-4021586 (150 mg, 300 mg, 450 mg, and 600 mg)
Drug: Placebo to match CK-4021586

This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD)...

Active, not recruiting
Atherosclerotic Cardiovascular Disease
Drug: Obicetrapib
Drug: Placebo

The primary objective of this trial is to demonstrate that maridebart cafraglutide is superior to placebo when given as an adjunct to standard of car...

Enrolling
Overweight
Atherosclerotic Cardiovascular Disease
Drug: Maridebart Cafraglutide
Drug: Placebo

The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipi...

Active, not recruiting
Stroke
Myocardial Infarction
Drug: Evolocumab
Drug: Routine Lipid Management

This study will examine if maridebart cafraglutide as an adjunct to standard of care will lead to a reduction in heart failure (HF) events such as HF...

Enrolling
Heart Failure With Preserved Ejection Fraction
Obesity
Drug: Placebo
Drug: Maridebart cafraglutide

Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants...

Active, not recruiting
Atherosclerotic Cardiovascular Disease
Drug: Placebo
Drug: Inclisiran sodium 300 mg

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