University of Massachusetts | Chan Medical School - Aaron Lazare Medical Research Building - Dermatology Department

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364 Plantation Street, LRB 1002, Worcester, Massachusetts, United States of America
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Aneurysm (10 trials)

Stroke (6 trials)

Aortic Aneurysm (6 trials)

Schizophrenia (5 trials)

Iliac Aneurysm (5 trials)

Top treatments


Data sourced from clinicaltrials.gov

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23 of 98
Status: Active
Trial type: Interventional
Funder type: Industry

A Phase 2 Study of Mirvetuximab Soravtansine (IMGN853) and Pembrolizumab in Endometrial Cancer (EC)

This research study is studying a drug combination as a possible treatment for endometrial cancer.The drugs involved in this study are:mirvetuximab s...

Endometrial Cancer
Drug: IMGN853
Drug: Pembrolizumab

The SUMMIT MAX study is a prospective, randomized, controlled, interventional clinical trial to evaluate the safety and effectiveness of the Route 92...

Active, not recruiting
Acute Ischemic Stroke
Device: Route 92 Medical Reperfusion System

This Phase 3 study is designed to compare the efficacy and safety of mirvetuximab soravtansine vs. investigator's choice chemotherapy in patients wit...

Active, not recruiting
Epithelial Ovarian Cancer
Peritoneal Cancer
Drug: Paclitaxel
Drug: Pegylated liposomal doxorubicin

This is a randomized, double-blind, placebo-controlled adaptive study of the safety, tolerability, and exploratory efficacy of once-daily topical WST...

Chemotherapy-induced Peripheral Neuropathy
Drug: WST-057 Active
Drug: Placebo

The primary objective of this study is to evaluate the long-term safety and tolerability of litifilimab in participants with active systemic lupus er...

Systemic Lupus Erythematosus (SLE)
Drug: Litifilimab-matching placebo
Drug: Litifilimab

In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). T...

Lupus Erythematosus, Systemic
Drug: Litifilimab
Drug: Placebo

The purpose of this study is to compare any good and bad effects of using radium-223 along with docetaxel chemotherapy treatment versus using docetax...

Prostate Cancer
Drug: Radium-223
Drug: Docetaxel 60 mg/m2

This is a phase II single arm trial to determine the percentage of patients without evidence of disease progression on abemaciclib and letrozole in a...

Active, not recruiting
Endometrial Cancer
Drug: Abemaciclib
Drug: Letrozole

To evaluate safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for transcatheter aortic valve replacement (TAVR) in subjects wi...

Aortic Stenosis
Device: ACURATE neo2™ Transfemoral TAVR System
Device: Edwards SAPIEN 3 TAVR System

The purpose of this Phase 3 study is to evaluate the efficacy and safety of Luspatercept compared with placebo in subjects with myeloproliferative ne...

Other: Placebo
Drug: ACE-536

Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Rest...

Dilated Cardiomyopathy
Heart Failure With Reduced Ejection Fraction (HFrEF)
Device: AccuCinch Ventricular Restoration System
Drug: Guideline-Directed Medical Therapy

The purpose of this clinical trial is to assess and evaluate the safety and efficacy of the Treovance Stent-Graft with Navitel Delivery System in sub...

Active, not recruiting
Abdominal Aortic Aneurysm (AAA)
Device: Subjects who receive the Treovance stent-graft

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) or AML secondary to prior myelodyspl...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Placebo
Drug: Oral Azacitidine

This is a Phase 3, randomized, double-blind trial to evaluate the efficacy and safety of neoadjuvant treatment with pamrevlumab or placebo in combina...

Active, not recruiting
Pancreatic Cancer Non-resectable
Drug: Pamrevlumab + Gemcitabine + Nab-paclitaxel or Pamrevlumab + FOLFIRINOX
Drug: Placebo + Gemcitabine + Nab-paclitaxel or Placebo + FOLFIRINOX

Contrast-Induced Nephropathy (CIN) can occur when patients with pre-existing kidney problems undergo procedures that use iodinated contrast media, su...

Active, not recruiting
Contrast Induced Nephropathy
Drug: Standard Therapy
Device: RenalGuard Therapy

The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resecti...

Colorectal Neoplasms
Drug: SGM-101

This is a randomized, open-label study. Patients will be screened within 28 days prior to the study drug administration. Patients will be randomly as...

Multiple Myeloma
Drug: GPC-100
Drug: G-CSF

The Phoenix Trial is a randomized double blind placebo controlled Phase III trial to evaluate the safety and efficacy of AMX0035 for treatment of ALS

Active, not recruiting
Amyotrophic Lateral Sclerosis
Drug: AMX0035
Other: Placebo

To evaluate repigmentation and quality of life after treatment of stable vitiligo lesions using the RECELL Device.

Active, not recruiting
Device: RECELL® Autologous Cell Harvesting Device

Afuresertib is an AKT inhibitor, a new class of agents under development that may provide physicians with a new clinical option to control platinum r...

Active, not recruiting
Platinum-resistant Ovarian Cancer
Drug: Afuresertib
Drug: Paclitaxel

Trial sponsors


University of Massachusetts, Worcester (6 trials)

Celgene logo

Celgene (4 trials)

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