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Find clinical trials for Adenocarcinoma in Louisville, KY

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Related conditions:

Carcinoma
Cancer
Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Esophageal Cancer
Non-Small-Cell Lung Carcinoma

Adenocarcinoma trials near Louisville, KY, USA:

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) (TroFuse-015)

(TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumote...

Enrolling
Gastroesophageal Cancer
Drug: Rescue medication
Drug: Supportive care measures

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Louisville, Kentucky, United States and 113 other locations

esophageal adenocarcinoma.This substudy will have two phases: a safety lead-in phase and an efficacy phase. The safety lead-in phase will b...

Enrolling
Gastroesophageal Adenocarcinoma
Esophageal Cancer
Drug: Levoleucovorin
Drug: Capecitabine

Phase 1, Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Louisville, Kentucky, United States and 18 other locations

and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropy...

Enrolling
Metastatic Pancreatic Adenocarcinoma
Drug: Capecitabine
Drug: Ivaltinostat

Phase 1, Phase 2

CG Pharmaceuticals

Louisville, Kentucky, United States and 19 other locations

the treatment of participants with advanced or metastatic gastric adenocarcinoma, gastroesophageal junction (GEJ) adenocarcinoma, o...

Enrolling
Gastroesophageal Adenocarcinoma
Esophageal Cancer
Biological: Ramucirumab
Drug: Paclitaxel

Phase 1, Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Louisville, Kentucky, United States and 21 other locations

first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

Phase 3

Arcus Biosciences
Arcus Biosciences

Louisville, Kentucky, United States and 203 other locations

Pancreatic cancer is difficult to diagnose early. By the time people have been diagnosed, the cancer has usually spread to other parts of the body (m...

Enrolling
Metastatic Pancreatic Adenocarcinoma
Drug: mFOLFIRINOX
Drug: zolbetuximab

Phase 1

Astellas
Astellas

Louisville, Kentucky, United States and 4 other locations

unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical st...

Active, not recruiting
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: fluorouracil
Drug: zolbetuximab

Phase 3

Astellas
Astellas

Louisville, Kentucky, United States and 219 other locations

The purpose of this study is to assess the efficacy and safety of lenvatinib (E7080/MK-7902) plus pembrolizumab (MK-3475) plus chemotherapy compared...

Active, not recruiting
Advanced/Metastatic Gastroesophageal Adenocarcinoma
Drug: 5-FU
Biological: Lenvatinib

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Louisville, Kentucky, United States of America and 176 other locations

Subjects will be offered the opportunity to participate in a randomized, controlled, 2-arm, unblinded multicenter trial (RCT). There will be 2 study...

Enrolling
Stage III Pancreatic Cancer
Drug: Modified FOLFIRINOX Regimen
Device: NanoKnife System

Phase 3

AngioDynamics
AngioDynamics

Louisville, Kentucky, United States and 5 other locations

A phase IIb, open-label, randomized study of Nab-Paclitaxel and Gemcitabine and plus/minus VCN-01 in Patients with Metastatic Pancreatic Cancer

Active, not recruiting
Pancreatic Adenocarcinoma
Metastatic
Genetic: VCN-01
Drug: Gemcitabine

Phase 2

Theriva Biologics

Louisville, Kentucky, United States and 16 other locations

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