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activity of CBI-1214 in participants with advanced or metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer...
Phase 1
San Antonio, Texas, United States and 9 other locations
This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...
Phase 1
San Antonio, Texas, United States of America and 32 other locations
This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...
Phase 1
San Antonio, Texas, United States and 16 other locations
This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012,...
Phase 1
San Antonio, Texas, United States and 25 other locations
The purpose of this study is to learn about the safety and effects of the study medicine when given alone or together with other anti-cancer...
Phase 1
San Antonio, Texas, United States of America and 12 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Phase 1, Phase 2
San Antonio, Texas, United States and 20 other locations
This study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors.
Phase 1, Phase 2
San Antonio, Texas, United States and 5 other locations
This is a Phase 1, first-in-human (FIH), open-label, multicenter study designed to evaluate the safety, tolerability, PK, and preliminary anti-tumor...
Phase 1
San Antonio, Texas, United States and 3 other locations
This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer...
Phase 1, Phase 2
San Antonio, Texas, United States and 13 other locations
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of escalating doses of RMC-6291 (KRAS G12C(ON) inhibitor...
Phase 1
San Antonio, Texas, United States and 63 other locations
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