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A) vs. mFOLFIRINOX plus placebo (Arm B) in 94 subjects with advanced pancreatic cancer, not amenable to curative treatment. Both ar...
Phase 2
Indianapolis, Indiana, United States and 7 other locations
phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...
Phase 1
Indianapolis, Indiana, United States and 55 other locations
This trial will study tisotumab vedotin to find out whether it is an effective treatment alone or with other anticancer drugs for certain solid tumors...
Phase 2
Indianapolis, Indiana, United States and 71 other locations
The purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161 as a single agent and in combination with pembrolizumab.
Phase 1
Indianapolis, Indiana, United States and 22 other locations
irinotecan (nal-IRI) with oxaliplatin, leucovorin, and 5-fluorouracil (FOLFOX-nal-IRI) for treatment of patients with locally advanced pancreatic...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific gen...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 49 other locations
deruxtecan (T-DXd) for the treatment of selected HER2-expressing tumors.This study will consist of Part 1 which includes 7 cohorts of: uroth ...
Phase 2
Muncie, Indiana, United States and 120 other locations
with recurrent, progressive, or refractory melanoma or other solid tumors with alterations in the key proteins of the RAS/RAF/MEK/ERK pathwa...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 19 other locations
activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in participants with KRAS G12D-mutant advanced solid tumor...
Phase 1
Indianapolis, Indiana, United States and 42 other locations
The study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigali...
Phase 1
Indianapolis, Indiana, United States and 53 other locations
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