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Find clinical trials for Pancreatic Cancer in Indianapolis, IN

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Indianapolis, IN, USA:

Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer

A) vs. mFOLFIRINOX plus placebo (Arm B) in 94 subjects with advanced pancreatic cancer, not amenable to curative treatment. Both ar...

Active, not recruiting
Pancreatic Cancer
Drug: Ramucirumab
Other: Placebo

Phase 2

Walid Shaib, MD

Indianapolis, Indiana, United States and 7 other locations

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: Gemcitabine
Drug: AMG 193

Phase 1

Amgen
Amgen

Indianapolis, Indiana, United States and 44 other locations

This trial will study tisotumab vedotin to find out whether it is an effective treatment alone or with other anticancer drugs for certain solid tumors...

Enrolling
Exocrine Pancreatic Cancer
Colorectal Neoplasms
Drug: cisplatin
Drug: carboplatin

Phase 2

Seagen
Seagen

Indianapolis, Indiana, United States and 71 other locations

The purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161 as a single agent and in combination with pembrolizumab.

Enrolling
Endometrial Cancer
Breast Cancer
Drug: Pembrolizumab
Drug: IDE-161

Phase 1

Ideaya Biosciences

Indianapolis, Indiana, United States and 22 other locations

the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ABM-168 in adult patients with RAS or RAF or NF-1 mutated ...

Enrolling
Advanced Solid Tumor
NF1 Mutation
Drug: ABM-168

Phase 1

ABM Therapeutics

Indianapolis, Indiana, United States and 5 other locations

irinotecan (nal-IRI) with oxaliplatin, leucovorin, and 5-fluorouracil (FOLFOX-nal-IRI) for treatment of patients with locally advanced pancreatic...

Active, not recruiting
Locally Advanced Pancreatic Carcinoma(LAPC)
Drug: FOLFOX regimen
Drug: Liposomal Irinotecan

Phase 2

Nelson Yee

Indianapolis, Indiana, United States and 3 other locations

The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific gen...

Enrolling
Ovarian Neoplasms
Biliary Tract Neoplasms
Drug: Cetuximab
Drug: Cisplatin

Phase 1, Phase 2

Lilly
Lilly

Indianapolis, Indiana, United States and 49 other locations

Locations recently updated

deruxtecan (T-DXd) for the treatment of selected HER2-expressing tumors.This study will consist of Part 1 which includes 7 cohorts of: uroth ...

Enrolling
Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer
Drug: Trastuzumab deruxtecan

Phase 2

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 120 other locations

Locations recently updated

and effective in participants with advanced, or metastatic solid tumors including urothelial cancer. The study is conducted in two ...

Enrolling
Esophageal Cancer
Advanced Solid Tumor
Drug: LY4052031

Phase 1

Lilly
Lilly

Indianapolis, Indiana, United States and 14 other locations

with recurrent, progressive, or refractory melanoma or other solid tumors with alterations in the key proteins of the RAS/RAF/MEK/ERK pathwa...

Active, not recruiting
Solid Tumor
Non Small Cell Lung Cancer
Drug: Tovorafenib
Drug: Pimasertib

Phase 1, Phase 2

Day One Biopharmaceuticals

Indianapolis, Indiana, United States and 19 other locations

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