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Find clinical trials for Pancreatic Cancer in Indianapolis, IN

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Lung Cancer
Non-Small-Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Indianapolis, IN, USA:

Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced Pancreatic Cancer (LAPIS)

with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of participants with locally advanced, unresectable pancreatic...

Active, not recruiting
Pancreatic Cancer Non-resectable
Drug: Pamrevlumab + Gemcitabine + Nab-paclitaxel or Pamrevlumab + FOLFIRINOX
Drug: Placebo + Gemcitabine + Nab-paclitaxel or Placebo + FOLFIRINOX

Phase 3

FibroGen
FibroGen

Indianapolis, Indiana, United States and 89 other locations

Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer

A) vs. mFOLFIRINOX plus placebo (Arm B) in 94 subjects with advanced pancreatic cancer, not amenable to curative treatment. Both ar...

Active, not recruiting
Pancreatic Cancer
Drug: Ramucirumab
Drug: mFOLFIRINOX

Phase 2

Walid Shaib, MD

Indianapolis, Indiana, United States and 7 other locations

Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors (innovaTV 207)

This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted eff...

Enrolling
Exocrine Pancreatic Cancer
Carcinoma, Non-Small-Cell Lung
Drug: cisplatin
Drug: carboplatin

Phase 2

Seagen
Seagen

Indianapolis, Indiana, United States and 60 other locations

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors (PAVO)

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI

Indianapolis, Indiana, United States and 79 other locations

Safety and Effectiveness of ABM-168 in Adults With Advanced Solid Tumors.

This is a Phase 1, First-in-Human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, phar...

Enrolling
NF1 Mutation
Advanced Solid Tumor
Drug: ABM-168

Phase 1

ABM Therapeutics

Indianapolis, Indiana, United States and 5 other locations

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors (DPT02)

consist of Part 1 which includes 7 cohorts of: urothelial bladder cancer, biliary tract cancer, cervical cancer, endometri ...

Active, not recruiting
Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer
Drug: Trastuzumab deruxtecan

Phase 2

AstraZeneca
AstraZeneca

Muncie, Indiana, United States and 76 other locations

Liposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:

irinotecan (nal-IRI) with oxaliplatin, leucovorin, and 5-fluorouracil (FOLFOX-nal-IRI) for treatment of patients with locally advanced pancreatic...

Active, not recruiting
Locally Advanced Pancreatic Carcinoma(LAPC)
Drug: FOLFOX regimen
Drug: Liposomal Irinotecan

Phase 2

Nelson Yee

Indianapolis, Indiana, United States and 3 other locations

Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors

The study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigali...

Enrolling
Advanced Solid Tumors Cancer
Drug: Livmoniplimab
Drug: Budigalimab

Phase 1

AbbVie
AbbVie

Indianapolis, Indiana, United States and 38 other locations

AMG 193, Methylthioadenosine (MTA) Cooperative Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor, Alone and in Combination With Docetaxel in Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors

The primary objective of Parts 1 and 2 of this study is to evaluate the safety, tolerability, and to determine the maximum tolerated dose (MTD) or re...

Enrolling
Advanced MTAP-null Solid Tumors
Drug: Docetaxel
Drug: AMG 193

Phase 1, Phase 2

Amgen
Amgen

Indianapolis, Indiana, United States and 52 other locations

Tovorafenib (DAY101) Monotherapy or in Combination With Other Therapies for Patients With Melanoma and Other Solid Tumors

This is a Phase 1b/2, multi-center, open label umbrella study of patients ≥12 years of age with recurrent, progressive, or refractory melanoma or oth...

Enrolling
Non Small Cell Lung Cancer
Bladder Cancer
Drug: Pimasertib
Drug: Tovorafenib

Phase 1, Phase 2

Day One Biopharmaceuticals

Indianapolis, Indiana, United States and 20 other locations

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